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Hyperleptinemia prevents lipotoxic cardiomyopathy in acyl CoA synthase transgenic mice

The physiologic function of the progressive hyperleptinemia of diet-induced obesity is unknown. However, that lipotoxicity in nonadipose tissues of congenitally unleptinized obese rodents is far greater than in hyperleptinemic diet-induced obesity rodents has suggested an antilipotoxic role. To test...

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Detalhes bibliográficos
Main Authors: Lee, Young, Naseem, R. Haris, Duplomb, Laurence, Park, Byung-Hyun, Garry, Daniel J., Richardson, James A., Schaffer, Jean E., Unger, Roger H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC518804/
https://ncbi.nlm.nih.gov/pubmed/15347805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0405499101
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