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Sulfate contributes to the negative charge of podocalyxin, the major sialoglycoprotein of the glomerular filtration slits.

Podocalyxin is the major sialoprotein of the rat glomerulus. Its function is to maintain the filtration slits of the glomerular epithelium open by virtue of its high net negative charge. We have used biosynthetic labeling and oligosaccharide analysis to characterize the anionic-charge-carrying moiet...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Dekan, G, Gabel, C, Farquhar, M G
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1991
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51880/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2052617/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.12.5398
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