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Activating calcium-sensing receptor mutation in the mouse is associated with cataracts and ectopic calcification

The extracellular calcium-sensing receptor (CaSR) plays a pivotal role in the regulation of extracellular calcium such that abnormalities, which result in a loss or gain of function, lead to hypercalcemia or hypocalcemia, respectively, in patients. Mice carrying CaSR knockout alleles develop hyperca...

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Detalhes bibliográficos
Main Authors: Hough, Tertius A., Bogani, Debora, Cheeseman, Michael T., Favor, Jack, Nesbit, M. Andrew, Thakker, Rajesh V., Lyon, Mary F.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC518795/
https://ncbi.nlm.nih.gov/pubmed/15347804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0405516101
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