A Novel Pathogenic BRCA1 Splicing Variant Produces Partial Intron Retention in the Mature Messenger RNA

About 10% of all breast cancers arise from hereditary mutations that increase the risk of breast and ovarian cancers; and about 25% of these are associated with the BRCA1 or BRCA2 genes. The identification of BRCA1/BRCA2 mutations can enable physicians to better tailor the clinical management of pat...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Esposito, Maria Valeria, Nunziato, Marcella, Starnone, Flavio, Telese, Antonella, Calabrese, Alessandra, D’Aiuto, Giuseppe, Pucci, Pietro, D’Aiuto, Massimiliano, Baralle, Francisco, D’Argenio, Valeria, Salvatore, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5187945/
https://ncbi.nlm.nih.gov/pubmed/28009814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17122145
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados