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Ribosomal protein S1 binds mRNA and tmRNA similarly but plays distinct roles in translation of these molecules

Ribosomes stalled during protein synthesis can be rescued by tmRNA, which acts first as a tRNA and then as an mRNA to direct addition of a C-terminal degradation tag to the nascent polypeptide. Ribosomal protein S1 binds tmRNA, but its functional role in tmRNA-mediated tagging is uncertain. To probe...

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Autores principales: McGinness, Kathleen E., Sauer, Robert T.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC518778/
https://ncbi.nlm.nih.gov/pubmed/15340139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0405521101
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