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Reversible inactivation of the insular cortex by tetrodotoxin produces retrograde and anterograde amnesia for inhibitory avoidance and spatial learning.

Tetrodotoxin (TTX; a voltage-sensitive sodium channel blocker) was microinjected bilaterally into the insular (IC), frontal (FC), or parietal (PC) cortex or the ventral caudate nucleus of rats either before or after they were trained in an inhibitory avoidance task. When administered either before o...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Bermudez-Rattoni, F, Introini-Collison, I B, McGaugh, J L
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1991
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51876/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2052615/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.12.5379
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