A bromodomain–DNA interaction facilitates acetylation-dependent bivalent nucleosome recognition by the BET protein BRDT

Bromodomains are critical components of many chromatin modifying/remodelling proteins and are emerging therapeutic targets, yet how they interact with nucleosomes, rather than acetylated peptides, remains unclear. Using BRDT as a model, we characterized how the BET family of bromodomains interacts w...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Nat Commun
Autors principals: Miller, Thomas C. R., Simon, Bernd, Rybin, Vladimir, Grötsch, Helga, Curtet, Sandrine, Khochbin, Saadi, Carlomagno, Teresa, Müller, Christoph W.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5187433/
https://ncbi.nlm.nih.gov/pubmed/27991587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13855
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars