Inactivation of Sonic Hedgehog Signaling and Polydactyly in Limbs of Hereditary Multiple Malformation, a Novel Type of Talpid Mutant

Hereditary Multiple Malformation (HMM) is a naturally occurring, autosomal recessive, homozygous lethal mutation found in Japanese quail. Homozygote embryos (hmm(−/−)) show polydactyly similar to talpid(2) and talpid(3) mutants. Here we characterize the molecular profile of the hmm(−/−) limb bud and...

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Detaylı Bibliyografya
Yayımlandı:Front Cell Dev Biol
Asıl Yazarlar: Matsubara, Yoshiyuki, Nakano, Mikiharu, Kawamura, Kazuki, Tsudzuki, Masaoki, Funahashi, Jun-Ichi, Agata, Kiyokazu, Matsuda, Yoichi, Kuroiwa, Atsushi, Suzuki, Takayuki
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2016
Konular:
Cell and Developmental Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5187386/
https://ncbi.nlm.nih.gov/pubmed/28083533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2016.00149
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