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Lenti in red: progress in gene therapy for human hemoglobinopathies

Hemoglobinopathies are caused by abnormal structure or synthesis of hemoglobin chains and represent serious monogenic disorders. A new study demonstrates that lentiviral vectors can express clinically relevant levels of human transgenic β-globin in red cells of xenografted mice. While some safety co...

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Detalhes bibliográficos
Main Authors: von Kalle, Christof, Baum, Christopher, Williams, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC518672/
https://ncbi.nlm.nih.gov/pubmed/15467825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200423132
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