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IRS2 takes center stage in the development of type 2 diabetes
The etiology of type 2 diabetes is characterized by obesity, insulin and leptin resistance, and compensatory β cell hyperplasia followed by islet degeneration, resulting in the eventual dysregulation of glucose and lipid homeostasis. The recent identification of insulin receptor substrate 2 (IRS2) a...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Clinical Investigation
2004
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC518671/ https://ncbi.nlm.nih.gov/pubmed/15467824 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200423108 |
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