The retinoblastoma gene functions as a growth and tumor suppressor in human bladder carcinoma cells.

The product of the human retinoblastoma gene (RB) is a nuclear phosphoprotein that is thought to function as a tumor suppressor. Mutations of RB frequently occur in human bladder carcinoma. To investigate the significance of the functional loss of this gene in bladder cancer, an RB expression plasmi...

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Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Takahashi, R, Hashimoto, T, Xu, H J, Hu, S X, Matsui, T, Miki, T, Bigo-Marshall, H, Aaronson, S A, Benedict, W F
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 1991
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51851/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2052605/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.12.5257
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