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Switching Roles of TGF-β in Cancer Development: Implications for Therapeutic Target and Biomarker Studies
TGF-β induces complicated and even opposite responses in numerous biological processes, e.g., tumor suppression in pre-malignant cells and metastasis promotion in cancer cells. However, the cellular contextual determinants of these different TGF-β roles remain elusive, and the driver genes triggerin...
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Publicado no: | J Clin Med |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
MDPI
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5184782/ https://ncbi.nlm.nih.gov/pubmed/27916872 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm5120109 |
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