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Switching Roles of TGF-β in Cancer Development: Implications for Therapeutic Target and Biomarker Studies

TGF-β induces complicated and even opposite responses in numerous biological processes, e.g., tumor suppression in pre-malignant cells and metastasis promotion in cancer cells. However, the cellular contextual determinants of these different TGF-β roles remain elusive, and the driver genes triggerin...

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Bibliographic Details
Published in:J Clin Med
Main Authors: Sun, Nan, Taguchi, Ayumu, Hanash, Samir
Format: Artigo
Language:Inglês
Published: MDPI 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5184782/
https://ncbi.nlm.nih.gov/pubmed/27916872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm5120109
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