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Dihydropyrimidine dehydrogenase mutation in neoadjuvant chemotherapy in head and neck cancers: Myth or reality?

PURPOSE: The docetaxel, 5-fluorouracil (5-FU), and cisplatin (TPF) regimen in India is associated with high percentages of Grade 3–4 toxicity. This analysis was planned to evaluate the incidence of dihydropyrimidine dehydrogenase (DPD) mutation in patients with severe gastrointestinal toxicity, to a...

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Détails bibliographiques
Publié dans:South Asian J Cancer
Auteurs principaux: Patil, Vijay M., Noronha, Vanita, Joshi, Amit, Zanwar, Saurabh, Ramaswamy, Anant, Arya, Supreeta, Mahajan, Abhishek, Bhattacharjee, Atanu, Prabhash, Kumar
Format: Artigo
Langue:Inglês
Publié: Medknow Publications & Media Pvt Ltd 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5184753/
https://ncbi.nlm.nih.gov/pubmed/28032083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2278-330X.195338
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