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2-deoxyglucose inhibits induction of chemokine expression in 3T3-L1 adipocytes and adipose tissue explants

OBJECTIVE: We sought to determine the influence of glycolytic inhibition on the adipocyte inflammatory response. METHODS: To determine the effect of 2-deoxyglucose (2-DOG) on the inflammatory response, mature 3T3-L1 adipocytes were co-treated with 2-DOG and LPS or TNF. To determine the effect of end...

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Detalhes bibliográficos
Publicado no:Obesity (Silver Spring)
Main Authors: Grant, Ryan W., Boudreaux, Jacqueline I., Stephens, Jacqueline M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5182088/
https://ncbi.nlm.nih.gov/pubmed/27706923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/oby.21668
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