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Genome-wide interrogation reveals hundreds of long intergenic noncoding RNAs that associate with cardiometabolic traits

Long intergenic noncoding RNAs (lincRNAs) play important roles in disease, but the vast majority of these transcripts remain uncharacterized. We defined a set of 54 944 human lincRNAs by drawing on four publicly available lincRNA datasets, and annotated ∼2.5 million single nucleotide polymorphisms (...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Ballantyne, Rachel L., Zhang, Xuan, Nuñez, Sara, Xue, Chenyi, Zhao, Wei, Reed, Eric, Salaheen, Danish, Foulkes, Andrea S., Li, Mingyao, Reilly, Muredach P.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5181595/
https://ncbi.nlm.nih.gov/pubmed/27288454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw154
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