HIV-1 drug resistance mutations emerging on darunavir therapy in PI-naive and -experienced patients in the UK

BACKGROUND: Darunavir is considered to have a high genetic barrier to resistance. Most darunavir-associated drug resistance mutations (DRMs) have been identified through correlation of baseline genotype with virological response in clinical trials. However, there is little information on DRMs that a...

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Detalhes bibliográficos
Publicado no:J Antimicrob Chemother
Main Authors: El Bouzidi, Kate, White, Ellen, Mbisa, Jean L., Sabin, Caroline A., Phillips, Andrew N., Mackie, Nicola, Pozniak, Anton L., Tostevin, Anna, Pillay, Deenan, Dunn, David T.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5181398/
https://ncbi.nlm.nih.gov/pubmed/27856703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkw343
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