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The Role of Lipopolysaccharide Structure in Monocyte Activation and Cytokine Secretion

BACKGROUND: The lipopolysaccharide (LPS) molecule is composed of a hydrophobic lipid region (Lipid A), an oligosaccharide core, and an O-Antigen chain. Lipid A has been described as the molecular region responsible for inducing activation of immune cells. We hypothesize that the O-Antigen plays a cr...

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Detalhes bibliográficos
Publicado no:Shock
Main Authors: Plevin, Rebecca E., Knoll, Megan, McKay, Meghan, Arbabi, Saman, Cuschieri, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5181111/
https://ncbi.nlm.nih.gov/pubmed/26674452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000000470
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