Allosteric transitions of the acetylcholine receptor probed at the amino acid level with a photolabile cholinergic ligand.

Structural changes occurring upon desensitization of the Torpedo marmorata acetylcholine receptor were monitored with tritiated p-(N,N-dimethyl)aminobenzenediazonium fluoroborate, a reversible competitive antagonist in the dark, which may serve as a photoaffinity probe of the area of the receptor mo...

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Bibliographic Details
Main Authors: Galzi, J L, Revah, F, Bouet, F, Ménez, A, Goeldner, M, Hirth, C, Changeux, J P
Format: Artigo
Language:Inglês
Published: 1991
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC51805/
https://ncbi.nlm.nih.gov/pubmed/2052586
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