Allosteric transitions of the acetylcholine receptor probed at the amino acid level with a photolabile cholinergic ligand.

Structural changes occurring upon desensitization of the Torpedo marmorata acetylcholine receptor were monitored with tritiated p-(N,N-dimethyl)aminobenzenediazonium fluoroborate, a reversible competitive antagonist in the dark, which may serve as a photoaffinity probe of the area of the receptor mo...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Galzi, J L, Revah, F, Bouet, F, Ménez, A, Goeldner, M, Hirth, C, Changeux, J P
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51805/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2052586/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.11.5051
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