Increase in circulating Th17 cells during anti-TNF therapy is associated with ultrasonographic improvement of synovitis in rheumatoid arthritis

BACKGROUND: Anti-TNF agents have revolutionised rheumatoid arthritis (RA) treatment; however, a third of patients fail to achieve therapeutic responses. Unexpectedly, studies in murine and human arthritis have indicated that anti-TNF treatment can increase circulating T helper 17 (Th17) cells, but t...

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Veröffentlicht in:Arthritis Res Ther
Hauptverfasser: Hull, Dobrina N., Cooksley, Helen, Chokshi, Shilpa, Williams, Richard O., Abraham, Sonya, Taylor, Peter C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5180397/
https://ncbi.nlm.nih.gov/pubmed/28010726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-016-1197-5
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