Translocation of the thioesterase domain for the redesign of plipastatin synthetase

Non-ribosomal peptide synthetases (NRPSs) are large enzymatic complexes that catalyse the synthesis of biologically active peptides in microorganisms. Genetic engineering has recently been applied to reprogram NRPSs to produce lipopeptides with a new sequence. The carboxyl-terminal thioesterase (TE)...

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Vydáno v:Sci Rep
Hlavní autoři: Gao, Ling, Liu, Hongxia, Ma, Zhi, Han, Jinzhi, Lu, Zhaoxin, Dai, Chen, Lv, Fengxia, Bie, Xiaomei
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5180189/
https://ncbi.nlm.nih.gov/pubmed/28009004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38467
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