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Driver gene classification reveals a substantial overrepresentation of tumor suppressors among very large chromatin-regulating proteins

Compiling a comprehensive list of cancer driver genes is imperative for oncology diagnostics and drug development. While driver genes are typically discovered by analysis of tumor genomes, infrequently mutated driver genes often evade detection due to limited sample sizes. Here, we address sample si...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Waks, Zeev, Weissbrod, Omer, Carmeli, Boaz, Norel, Raquel, Utro, Filippo, Goldschmidt, Yaara
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5180091/
https://ncbi.nlm.nih.gov/pubmed/28008934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38988
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