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Ambiguous allele combinations in HLA Class I and Class II sequence-based typing: when precise nucleotide sequencing leads to imprecise allele identification

Sequence-based typing (SBT) is one of the most comprehensive methods utilized for HLA typing. However, one of the inherent problems with this typing method is the interpretation of ambiguous allele combinations which occur when two or more different allele combinations produce identical sequences. T...

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Detalhes bibliográficos
Main Authors: Adams, Sharon D, Barracchini, Kathleen C, Chen, Deborah, Robbins, FuMeei, Wang, Lu, Larsen, Paula, Luhm, Robert, Stroncek, David F
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC517951/
https://ncbi.nlm.nih.gov/pubmed/15363110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-2-30
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