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Opening the Blood-Brain Barrier with MR Imaging–guided Focused Ultrasound: Preclinical Testing on a Trans–Human Skull Porcine Model

PURPOSE: To develop and test a protocol in preparation for a clinical trial on opening the blood-brain barrier (BBB) with magnetic resonance (MR) imaging–guided focused ultrasound for the delivery of chemotherapy drugs to brain tumors. MATERIALS AND METHODS: The procedures were approved by the insti...

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Detalhes bibliográficos
Publicado no:Radiology
Main Authors: Huang, Yuexi, Alkins, Ryan, Schwartz, Michael L., Hynynen, Kullervo
Formato: Artigo
Idioma:Inglês
Publicado em: Radiological Society of North America 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5179309/
https://ncbi.nlm.nih.gov/pubmed/27420647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1148/radiol.2016152154
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