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Establishment of a 3D In Vitro Model to Accelerate the Development of Human Therapies against Corneal Diabetes

PURPOSE: To establish an in vitro model that would mirror the in vivo corneal stromal environment in diabetes (DM) patients. METHODS: Human corneal fibroblasts from Healthy (HCFs), Type 1DM (T1DM) and Type 2DM (T2DM) donors were isolated and cultured for 4 weeks with Vitamin C stimulation in order t...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Priyadarsini, Shrestha, Sarker-Nag, Akhee, Rowsey, Tyler G., Ma, Jian-Xing, Karamichos, Dimitrios
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5179241/
https://ncbi.nlm.nih.gov/pubmed/28005998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0168845
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