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MTOR-Driven Metabolic Reprogramming Regulates Legionella pneumophila Intracellular Niche Homeostasis

Vacuolar bacterial pathogens are sheltered within unique membrane-bound organelles that expand over time to support bacterial replication. These compartments sequester bacterial molecules away from host cytosolic immunosurveillance pathways that induce antimicrobial responses. The mechanisms by whic...

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Bibliografiske detaljer
Udgivet i:PLoS Pathog
Main Authors: Abshire, Camille F., Dragoi, Ana-Maria, Roy, Craig R., Ivanov, Stanimir S.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5179073/
https://ncbi.nlm.nih.gov/pubmed/27942021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006088
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