Phosphatidylinositol-4,5-Bisphosphate-Rich Plasma Membrane Patches Organize Active Zones of Endocytosis and Ruffling in Cultured Adipocytes

A major regulator of endocytosis and cortical F-actin is thought to be phosphatidylinositol-4,5-bisphosphate [PtdIns(4,5)P(2)] present in plasma membranes. Here we report that in 3T3-L1 adipocytes, clathrin-coated membrane retrieval and dense concentrations of polymerized actin occur in restricted z...

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Detalles Bibliográficos
Main Authors: Huang, Shaohui, Lifshitz, Larry, Patki-Kamath, Varsha, Tuft, Richard, Fogarty, Kevin, Czech, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2004
Assuntos:
Cell Growth and Development
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC517906/
https://ncbi.nlm.nih.gov/pubmed/15456883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.20.9102-9123.2004
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