CD4/CD8 Ratio and KT Ratio Predict Yellow Fever Vaccine Immunogenicity in HIV-Infected Patients

BACKGROUND: HIV-infected individuals have deficient responses to Yellow Fever vaccine (YFV) and may be at higher risk for adverse events (AE). Chronic immune activation–characterized by low CD4/CD8 ratio or high indoleamine 2,3-dioxygenase-1 (IDO) activity—may influence vaccine response in this popu...

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發表在:PLoS Negl Trop Dis
Main Authors: Avelino-Silva, Vivian I., Miyaji, Karina T., Hunt, Peter W., Huang, Yong, Simoes, Marisol, Lima, Sheila B., Freire, Marcos S., Caiaffa-Filho, Helio H., Hong, Marisa A., Costa, Dayane Alves, Dias, Juliana Zanatta C., Cerqueira, Natalia B., Nishiya, Anna Shoko, Sabino, Ester Cerdeira, Sartori, Ana M., Kallas, Esper G.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2016
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5179051/
https://ncbi.nlm.nih.gov/pubmed/27941965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005219
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