Genetically Increasing Myoc Expression Supports a Necessary Pathologic Role of Abnormal Proteins in Glaucoma

Despite the importance of MYOC for glaucoma, the protein's normal function(s) and the pathogenic mechanism(s) of MYOC mutations are not clear. Elevated intraocular pressure (IOP) and glaucoma are sometimes induced by corticosteroids, and corticosteroid use can result in substantially increased...

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Detalhes bibliográficos
Main Authors: Gould, Douglas B., Miceli-Libby, Laura, Savinova, Olga V., Torrado, Mario, Tomarev, Stanislav I., Smith, Richard S., John, Simon W. M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC517885/
https://ncbi.nlm.nih.gov/pubmed/15456875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.20.9019-9025.2004
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