RNA Polymerase II Carboxy-Terminal Domain Phosphorylation Is Required for Cotranscriptional Pre-mRNA Splicing and 3′-End Formation

We investigated the role of RNA polymerase II (pol II) carboxy-terminal domain (CTD) phosphorylation in pre-mRNA processing coupled and uncoupled from transcription in Xenopus oocytes. Inhibition of CTD phosphorylation by the kinase inhibitors 5,6-dichloro-1β-d-ribofuranosyl-benzimidazole and H8 blo...

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Bibliographic Details
Main Authors: Bird, Gregory, Zorio, Diego A. R., Bentley, David L.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC517882/
https://ncbi.nlm.nih.gov/pubmed/15456870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.20.8963-8969.2004
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