NOD2 dependent neutrophil recruitment is required for early protective immune responses against infectious Litomosoides sigmodontis L3 larvae

Nucleotide-binding oligomerization domain-containing protein 2 (NOD2) recognizes muramyl dipeptide (MDP) of bacterial cell walls, triggering NFκB-induced pro-inflammation. As most human pathogenic filariae contain Wolbachia endobacteria that synthesize the MDP-containing cell wall precursor lipid II...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Ajendra, Jesuthas, Specht, Sabine, Ziewer, Sebastian, Schiefer, Andrea, Pfarr, Kenneth, Parčina, Marijo, Kufer, Thomas A., Hoerauf, Achim, Hübner, Marc P.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5177913/
https://ncbi.nlm.nih.gov/pubmed/28004792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39648
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