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A challenge to the striking genotypic heterogeneity of retinitis pigmentosa: a better understanding of the pathophysiology using the newest genetic strategies

Retinitis pigmentosa (RP) is a group of inherited retinal disorders characterized by a complex association between tremendous genotypic multiplicity and great phenotypic heterogeneity. The severity of the clinical manifestation depends on penetrance and expressivity of the disease-gene. Also, variou...

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Detalhes bibliográficos
Publicado no:Eye (Lond)
Main Authors: Sorrentino, F S, Gallenga, C E, Bonifazzi, C, Perri, P
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5177762/
https://ncbi.nlm.nih.gov/pubmed/27564722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/eye.2016.197
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