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Early Degeneration of Both Dopaminergic and Serotonergic Axons – A Common Mechanism in Parkinson’s Disease

Motor symptoms in Parkinson’s disease (PD) are tightly linked to the degeneration of substantia nigra dopaminergic neurons and their projections into the striatum. Moreover, a broad range of non-motor symptoms like anxiety and depression frequently occur in PD, most likely related to the loss of ser...

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Veröffentlicht in:Front Cell Neurosci
Hauptverfasser: Grosch, Janina, Winkler, Jürgen, Kohl, Zacharias
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5177648/
https://ncbi.nlm.nih.gov/pubmed/28066188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2016.00293
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