Vav Proteins Are Key Regulators of Card9 Signaling for Innate Antifungal Immunity

Fungal infections are major causes of morbidity and mortality, especially in immunocompromised individuals. The innate immune system senses fungal pathogens through Syk-coupled C-type lectin receptors (CLRs), which signal through the conserved immune adaptor Card9. Although Card9 is essential for an...

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Опубликовано в: :Cell Rep
Главные авторы: Roth, Susanne, Bergmann, Hanna, Jaeger, Martin, Yeroslaviz, Assa, Neumann, Konstantin, Koenig, Paul-Albert, Prazeres da Costa, Clarissa, Vanes, Lesley, Kumar, Vinod, Johnson, Melissa, Menacho-Márquez, Mauricio, Habermann, Bianca, Tybulewicz, Victor L., Netea, Mihai, Bustelo, Xosé R., Ruland, Jürgen
Формат: Artigo
Язык:Inglês
Опубликовано: Cell Press 2016
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5177621/
https://ncbi.nlm.nih.gov/pubmed/27926862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.11.018
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