Complement Protein C1q Interacts with DC-SIGN via Its Globular Domain and Thus May Interfere with HIV-1 Transmission

Dendritic cells (DCs) are the most potent antigen-presenting cells capable of priming naïve T-cells. Its C-type lectin receptor, DC-SIGN, regulates a wide range of immune functions. Along with its role in HIV-1 pathogenesis through complement opsonization of the virus, DC-SIGN has recently emerged a...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Pednekar, Lina, Pandit, Hrishikesh, Paudyal, Basudev, Kaur, Anuvinder, Al-Mozaini, Maha Ahmed, Kouser, Lubna, Ghebrehiwet, Berhane, Mitchell, Daniel A., Madan, Taruna, Kishore, Uday
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5177617/
https://ncbi.nlm.nih.gov/pubmed/28066413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00600
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