IgA1 immune complex-mediated activation of MAPK/ERK kinase pathway in mesangial cells is associated with glomerular damage in IgA nephropathy

IgA nephropathy (IgAN) is the most common primary glomerulonephritis worldwide and has significant morbidity and mortality as 20–40% of patients progress to end-stage renal disease (ESRD) within 20 years after disease onset. We aimed to gain insight into the molecular mechanisms involved in IgAN pro...

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Publicat a:Kidney Int
Autors principals: Tamouza, Houda, Chemouny, Jonathan Maurice, Kafkova, Leona Raskova, Berthelot, Laureline, Flamant, Martin, Demion, Marie, Mesnard, Laurent, Walker, Francine, Julian, Bruce A., Tissandié, Emilie, Tiwari, Meetu Kaushik, Camara, Niels Olsen Saraiva, Vrtovsnik, François, Benhamou, Marc, Novak, Jan, Monteiro, Renato C., Moura, Ivan C.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5177564/
https://ncbi.nlm.nih.gov/pubmed/22951891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2012.192
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