IgA1 immune complex-mediated activation of MAPK/ERK kinase pathway in mesangial cells is associated with glomerular damage in IgA nephropathy

IgA nephropathy (IgAN) is the most common primary glomerulonephritis worldwide and has significant morbidity and mortality as 20–40% of patients progress to end-stage renal disease (ESRD) within 20 years after disease onset. We aimed to gain insight into the molecular mechanisms involved in IgAN pro...

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書誌詳細
出版年:Kidney Int
主要な著者: Tamouza, Houda, Chemouny, Jonathan Maurice, Kafkova, Leona Raskova, Berthelot, Laureline, Flamant, Martin, Demion, Marie, Mesnard, Laurent, Walker, Francine, Julian, Bruce A., Tissandié, Emilie, Tiwari, Meetu Kaushik, Camara, Niels Olsen Saraiva, Vrtovsnik, François, Benhamou, Marc, Novak, Jan, Monteiro, Renato C., Moura, Ivan C.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5177564/
https://ncbi.nlm.nih.gov/pubmed/22951891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2012.192
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