Influence of Polymorphisms in the HTR3A and HTR3B Genes on Experimental Pain and the Effect of the 5-HT(3) Antagonist Granisetron

The aim of this study was to investigate experimentally if 5-HT(3) single nucleotide polymorphisms (SNP) contribute to pain perception and efficacy of the 5-HT(3)-antagonist granisetron and sex differences. Sixty healthy participants were genotyped regarding HTR3A (rs1062613) and HTR3B (rs1176744)....

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Pubblicato in:PLoS One
Autori principali: Louca Jounger, Sofia, Christidis, Nikolaos, Hedenberg-Magnusson, Britt, List, Thomas, Svensson, Peter, Schalling, Martin, Ernberg, Malin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5176308/
https://ncbi.nlm.nih.gov/pubmed/28002447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0168703
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