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Bone Morphogenetic Protein-2 Promotes Human Mesenchymal Stem Cell Survival and Resultant Bone Formation when Entrapped in Photocrosslinked Alginate Hydrogels

There is a substantial need for methods that prolong cell persistence and enhance functionality in situ to enhance cell-based tissue repair. Bone morphogenetic protein-2 (BMP-2) is often used at high concentrations for osteogenic differentiation of mesenchymal stem cells (MSCs) but can induce apopto...

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Publicat a:Adv Healthc Mater
Autors principals: Ho, Steve S., Vollmer, Nina L., Refaat, Motasem I., Jeon, Oju, Alsberg, Eben, Lee, Mark A., Leach, J. Kent
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5176258/
https://ncbi.nlm.nih.gov/pubmed/27581621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adhm.201600461
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