Abatacept in B7-1–Positive Proteinuric Kidney Disease

Abatacept (cytotoxic T-lymphocyte–associated antigen 4–immunoglobulin fusion protein [CTLA-4–Ig]) is a costimulatory inhibitor that targets B7-1 (CD80). The present report describes five patients who had focal segmental glomerulosclerosis (FSGS) (four with recurrent FSGS after transplantation and on...

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Udgivet i:N Engl J Med
Main Authors: Yu, Chih-Chuan, Fornoni, Alessia, Weins, Astrid, Hakroush, Samy, Maiguel, Dony, Sageshima, Junichiro, Chen, Linda, Ciancio, Gaetano, Faridi, Mohd. Hafeez, Behr, Daniel, Campbell, Kirk N., Chang, Jer-Ming, Chen, Hung-Chun, Oh, Jun, Faul, Christian, Arnaout, M. Amin, Fiorina, Paolo, Gupta, Vineet, Greka, Anna, Burke, George W., Mundel, Peter
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5176021/
https://ncbi.nlm.nih.gov/pubmed/24670178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMc1400502
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