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The ClpP Protease of Streptococcus pneumoniae Modulates Virulence Gene Expression and Protects against Fatal Pneumococcal Challenge

Streptococcus pneumoniae usually colonizes the nasopharynx of humans asymptomatically but occasionally translocates from this niche to the lungs, the brain, and the blood, causing potentially fatal infections. Spread to other host tissues requires a significant morphological change and the expressio...

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Main Authors: Kwon, Hyog-Young, Ogunniyi, A. David, Choi, Moo-Hyun, Pyo, Suhk-Neung, Rhee, Dong-Kwon, Paton, James C.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2004
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC517602/
https://ncbi.nlm.nih.gov/pubmed/15385462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.10.5646-5653.2004
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