Enhanced Lung Injury and Delayed Clearance of Pneumocystis carinii in Surfactant Protein A-Deficient Mice: Attenuation of Cytokine Responses and Reactive Oxygen-Nitrogen Species

Surfactant protein A (SP-A), a member of the collectin family, selectively binds to Pneumocystis carinii and mediates interactions between pathogen and host alveolar macrophages in vitro. To test the hypothesis that mice lacking SP-A have delayed clearance of Pneumocystis organisms and enhanced lung...

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Main Authors: Atochina, Elena N., Beck, James M., Preston, Angela M., Haczku, Angela, Tomer, Yaniv, Scanlon, Seth T., Fusaro, Trevor, Casey, John, Hawgood, Samuel, Gow, Andrew J., Beers, Michael F.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2004
Assuntos:
Fungal and Parasitic Infections
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC517574/
https://ncbi.nlm.nih.gov/pubmed/15385504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.10.6002-6011.2004
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