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Use of a rapid, efficient inoculation method to induce papillomas by cottontail rabbit papillomavirus DNA shows that the E7 gene is required.

A simple inoculation method to induce papillomas efficiently with cottontail rabbit papillomavirus (CRPV) DNA is described. Using a jet injector, recombinant CRPV DNA is easily delivered to 100 or more sites per rabbit and induces typical epithelial papillomas in approximately 50% of those sites. Pa...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Brandsma, J L, Yang, Z H, Barthold, S W, Johnson, E A
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1991
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51757/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1647019/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.11.4816
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