Sm14 of Schistosoma mansoni in Fusion with Tetanus Toxin Fragment C Induces Immunoprotection against Tetanus and Schistosomiasis in Mice

We have constructed vectors that permit the expression in Escherichia coli of Schistosoma mansoni fatty acid-binding protein 14 (Sm14) in fusion with the nontoxic, but highly immunogenic, tetanus toxin fragment C (TTFC). The recombinant six-His-tagged proteins were purified by nickel affinity chroma...

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Главные авторы: Abreu, Patrícia A. E., Miyasato, Patrícia A., Vilar, Mônica M., Dias, Waldely O., Ho, Paulo L., Tendler, Míriam, Nascimento, Ana L. T. O.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2004
Предметы:
Microbial Immunity and Vaccines
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC517564/
https://ncbi.nlm.nih.gov/pubmed/15385496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.10.5931-5937.2004
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