Protective Effect of a Tuberculosis Subunit Vaccine Based on a Fusion of Antigen 85B and ESAT-6 in the Aerosol Guinea Pig Model

A fusion protein of antigen 85B (Ag85B) and ESAT-6 administered in cationic lipid vesicles conferred a highly significant level of protection against Mycobacterium tuberculosis in the guinea pig aerosol model of infection. The protection was manifested as delayed clinical illness and prolonged survi...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Olsen, Anja W., Williams, Ann, Okkels, Limei M., Hatch, Graham, Andersen, Peter
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2004
Assuntos:	Microbial Immunity and Vaccines
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC517547/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15385521/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.72.10.6148-6150.2004
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