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Preclinical Evaluation of a Replication-Deficient Recombinant Adenovirus Serotype 5 Vaccine Expressing Guanylate Cyclase C and the PADRE T-helper Epitope

There is an unmet need for improved therapeutics for colorectal cancer, the second leading cause of cancer mortality worldwide. Adjuvant chemotherapy only marginally improves survival in some patients and has no benefit in others, underscoring the clinical opportunity for novel immunotherapeutic app...

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Detalhes bibliográficos
Publicado no:Hum Gene Ther Methods
Main Authors: Snook, Adam E., Baybutt, Trevor R., Hyslop, Terry, Waldman, Scott A.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5175423/
https://ncbi.nlm.nih.gov/pubmed/27903079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hgtb.2016.114
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