TRAF6-Dependent Mitogen-Activated Protein Kinase Activation Differentially Regulates the Production of Interleukin-12 by Macrophages in Response to Toxoplasma gondii

The production of interleukin-12 (IL-12) is critical to the development of innate and adaptive immune responses required for the control of intracellular pathogens. Many microbial products signal through Toll-like receptors (TLR) and activate NF-κB family members that are required for the production...

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Autors principals: Mason, Nicola J., Fiore, Jim, Kobayashi, Takashi, Masek, Katherine S., Choi, Yongwon, Hunter, Christopher A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
Matèries:
Fungal and Parasitic Infections
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC517541/
https://ncbi.nlm.nih.gov/pubmed/15385464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.10.5662-5667.2004
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