Misleading early blood volume changes obtained using ferumoxytol-based magnetic resonance imaging perfusion in high grade glial neoplasms treated with bevacizumab

BACKGROUND: Neovascularization, a distinguishing trait of high-grade glioma, is a target for anti-angiogenic treatment with bevacizumab (BEV). This study sought to use ferumoxytol-based dynamic susceptibility contrast magnetic resonance imaging (MRI) to clarify perfusion and relative blood volume (r...

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Detalhes bibliográficos
Publicado no:Fluids Barriers CNS
Main Authors: Netto, Joao Prola, Schwartz, Daniel, Varallyay, Csanad, Fu, Rongwei, Hamilton, Bronwyn, Neuwelt, Edward A.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5175388/
https://ncbi.nlm.nih.gov/pubmed/27998280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12987-016-0047-9
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