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The functional requirement of two structural domains within telomerase RNA emerged early in eukaryotes
Telomerase emerged during evolution as a prominent solution to the eukaryotic linear chromosome end-replication problem. Telomerase minimally comprises the catalytic telomerase reverse transcriptase (TERT) and telomerase RNA (TR) that provides the template for telomeric DNA synthesis. While the TERT...
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Publicado no: | Nucleic Acids Res |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5175330/ https://ncbi.nlm.nih.gov/pubmed/27378779 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw605 |
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