Overexcited MaxiK and K(ATP) channels underlie obstructive jaundice-induced vasoconstrictor hyporeactivity of arterial smooth muscle

Substantial evidence has shown that obstructive jaundice can induce vascular hyporesponsiveness. The present study was designed to investigate mechanisms of MaxiK channel and K(ATP) underlying cholestasis-induced vascular dysfunction. The isolated thoracic aorta was used to explore norepinephrine (N...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yuan, Ya-wei, Wang, Long, Lu, Zhan-ying, Long, Yue, Jiao, Ying-fu, Xia, Qiang, Wen, Da-xiang, Yu, Wei-feng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5175282/
https://ncbi.nlm.nih.gov/pubmed/28000721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39246
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