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Cooperative Interactions between Flagellin and SopE2 in the Epithelial Interleukin-8 Response to Salmonella enterica Serovar Typhimurium Infection

Flagellin is an important stimulus for epithelial interleukin-8 (IL-8) secretion because of its ability to activate Toll-like receptor 5 (TLR5). SopE2, a Salmonella guanine nucleotide exchange factor (GEF), is also involved in intestinal inflammation. To clarify the proinflammatory mechanisms of the...

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Main Authors: Huang, Fu-Chen, Werne, Adam, Li, Qian, Galyov, Edouard E., Walker, W. Allan, Cherayil, Bobby J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC517448/
https://ncbi.nlm.nih.gov/pubmed/15321998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.9.5052-5062.2004
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