Differential Monocyte Activation Underlies Strain-Specific Mycobacterium tuberculosis Pathogenesis

In vitro infection of monocytes with Mycobacterium tuberculosis HN878 and related W/Beijing isolates preferentially induced interleukin-4 (IL-4) and IL-13, which characterize Th2 polarized immunity. In contrast, CDC1551 induced more IL-12 and other molecules associated with phagocyte activation and...

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Detalhes bibliográficos
Main Authors: Manca, Claudia, Reed, Michael B., Freeman, Sherry, Mathema, Barun, Kreiswirth, Barry, Barry, Clifton E., Kaplan, Gilla
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC517425/
https://ncbi.nlm.nih.gov/pubmed/15322056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.9.5511-5514.2004
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