Differential Monocyte Activation Underlies Strain-Specific Mycobacterium tuberculosis Pathogenesis

In vitro infection of monocytes with Mycobacterium tuberculosis HN878 and related W/Beijing isolates preferentially induced interleukin-4 (IL-4) and IL-13, which characterize Th2 polarized immunity. In contrast, CDC1551 induced more IL-12 and other molecules associated with phagocyte activation and...

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Опубликовано в: :Infect Immun
Главные авторы: Manca, Claudia, Reed, Michael B., Freeman, Sherry, Mathema, Barun, Kreiswirth, Barry, Barry, Clifton E., Kaplan, Gilla
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 2004
Предметы:
Host Response and Inflammation
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC517425/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15322056/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.72.9.5511-5514.2004
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